Mahan Gholam Azad Selected Research

Neoplasms (Cancer)

1/2024	Differential transmetallation of complexes of the anti-cancer thiosemicarbazone, Dp4e4mT: effects on anti-proliferative efficacy, redox activity, oxy-myoglobin and oxy-hemoglobin oxidation.
1/2023	Innovative thiosemicarbazones that induce multi-modal mechanisms to down-regulate estrogen-, progesterone-, androgen- and prolactin-receptors in breast cancer.
1/2022	The thiosemicarbazone, DpC, broadly synergizes with multiple anti-cancer therapeutics and demonstrates temperature- and energy-dependent uptake by tumor cells.
10/2021	The Oncogenic Signaling Disruptor, NDRG1: Molecular and Cellular Mechanisms of Activity.
9/2021	The Relationship of Glutathione-S-Transferase and Multi-Drug Resistance-Related Protein 1 in Nitric Oxide (NO) Transport and Storage.

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Mahan Gholam Azad Research Topics

Disease

5	Neoplasms (Cancer) 01/2024 - 09/2021
1	Breast Neoplasms (Breast Cancer) 01/2023
1	Parkinson Disease (Parkinson's Disease) 11/2021
1	Lymphoma (Lymphomas) 10/2021
1	Neoplasm Metastasis (Metastasis) 10/2021

Drug/Important Bio-Agent (IBA)

4	ThiosemicarbazonesIBA 01/2024 - 10/2021
2	IronIBA 11/2021 - 09/2021
2	Proteins (Proteins, Gene)FDA Link 10/2021 - 09/2021
1	MyoglobinIBA 01/2024
1	Hemoglobins (Hemoglobin)IBA 01/2024
1	Progesterone FDA LinkGeneric 01/2023
1	Estrogens (Estrogen)FDA Link 01/2023
1	Prolactin Receptors (Prolactin Receptor)IBA 01/2023
1	Growth Factor ReceptorsIBA 01/2023
1	Tamoxifen FDA LinkGeneric 01/2023
1	AndrogensIBA 01/2023
1	Estrogen ReceptorsIBA 01/2023
1	di- 2- pyridylketone- 4,4- dimethyl- 3- thiosemicarbazoneIBA 01/2022
1	Sodium Fluoride (Ossin)FDA Link 01/2022
1	Calcium Channels (Calcium Channel)IBA 11/2021
1	Proto-Oncogene Proteins c-cblIBA 10/2021
1	tyrosine receptor (receptor, tyrosine)IBA 10/2021
1	Phosphotransferases (Kinase)IBA 10/2021
1	Tyrosine (L-Tyrosine)FDA Link 10/2021
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 10/2021
1	dithiolIBA 09/2021
1	Glutathione Transferase (Glutathione S-Transferase)IBA 09/2021

Therapy/Procedure

2	Therapeutics 01/2022 - 11/2021